At least 25 migrants have been killed this year by Egyptian police along the border with Israel [EPA]

Egyptian police spotted the six men, who are from Sudan and Eritrea, as they attempted to cross the border fence into Israel on Tuesday night.

Police said officers opened fire when the men failed to respond to an order to stop, hitting an Eritrean in the chest.

The man has been hospitalised and is in a serious condition.

The other five men were injured while trying to cross the barbed wire border fence and were also admitted to hospital.

Up to 25 migrants have been killed this year by Egyptian police along the 250km-long border with Israel.

African migrants in Egypt complain of poor treatment and discrimination, and hundreds have been arrested while trying to slip into Israel.

The border has become a major transit route for migrants, asylum-seekers and drug smugglers, prompting Israel to ask Cairo's help in clamping down on the traffic.

In August, Amnesty International urged the Egyptian government to launch an investigation into the use of lethal force against illegal migrants.

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